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How does letrozole work for PCOS? Letrozole is an aromatase inhibitor which prevents the conversion of androgen to estrogen. It also improves endometrial thickness and encourages healthy ovarian follicular development. While not approved by the FDA for this use, it has been shown to induce ovulation in women who do not ovulate.
Does a woman's fertility decrease with age? A woman's fertility starts to decline in her early 30s, with the decline speeding up after 35. Male fertility decline is more subtle, but a man's age affect the chances of his (female) partner conceiving, and increases the risk of miscarriage, and the child's risk of mental health and developmental disorders.
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